Aerpio(美國)

Aerpio Therapeutics

美國Aerpio www.aerpio.comAerpioTherapeutics公司宣布其作為一個獨立的臨床階段生物技術公司而開張，開發(fā)治療多種疾病的新型小分子Tie-2激動劑和HIF-1a穩(wěn)定劑。Aerpio公司是從AkebiaTherapeutics公司中剝離出來的AerpioTherapeuticsisanew,clinical-stagebiotechnologycompanyfocus edonthedevelopmentofnovelsmallmoleculesandmonoclonalantibodiesforthetreatmentofvasculardiseaseandenhancementofwoundhealing.Aerpiowascreatedinaspin-outtransactionfromAkebiaTherapeuticstoenablemorerapiddevelopmentofitsexcitingcompounds.ItismanagedbythesamesuccessfulteamfromAkebia,employingasimilaroutsourcedapproachtopharmaceuticaldevelopment.Aerpio'stwoleadprogramsincludeaTie-2activatorfordiabeticmacularedema(DME)andvascularleak,andaHypoxia-inducibleFactor1-α(HIF1-α)stabilizerforwoundhealingandthetreatmentofinflammatoryboweldisease.TheleadcompoundfortheTie-2program,AKB-9778,iscurrentlycompletingitsinitialPhase1clini