SAGE Therapeutics(美國)

SAGE Therapeutics

SAGETherapeuticswww.sagerx.com開發(fā)治療中樞神經(jīng)系統(tǒng)（CNS）疾病藥物SAGETherapeuticsisaneuroscience-focusedcompanydevelopingtherapiestotreatCNSspecialtyandorphandiseases.Thecompanyhasidentifiedseveralproductopportunitie swithclearandacceleratedpathstoregulatoryapproval.SAGE’sinitialpipelineincludesprogramsinstatusepilepticus,anesthesia,FragileXSyndromeandtraumaticbraininjury,whereCNSdrugspoorlyaddresstheareasofmosturgentpatientneedandareoftenaccompaniedbyconsiderablesideeffects.Thecompany’srobustallostericmodulatorchemistryplatform–calledthePositiveandNegativeAllostericModulator(PANAM)platform–hasgeneratedmultiplenewchemicalentitiessupportedbypromisingpreclinicaldatawiththepotentialtoleadtoproductswithmultipleindicationsoverthenextseveralyears.SAGETherapeuticsisaprivatecompanylaunchedin2011byaproventeamofR&Dleaders,renowned