KaloBios(美國(guó))

KaloBios Pharmaceuticals

美國(guó)KaloBiosPharmaceuticalswww.kalobios.comHumaneering（TM）是KaloBios制藥的專(zhuān)利治療方法，用于將非人體抗體轉(zhuǎn)為應(yīng)用于治療藥物的工程人體抗體。該系統(tǒng)具有保持抗原決定基特異性和提高親和性的優(yōu)點(diǎn)。KaloBios正在有限的基礎(chǔ)上提供利用humaneering（TM）功能的機(jī)會(huì)。KaloBiosPharmaceuticals,Inc.,aU.S. based,privatemonoclonalcompany,usesitsbiologiccapabilitiesanditsproprietaryplatformtechnologytodevelopfirst-in-classhumanantibodytherapeutics.ThecompanyhasmultipleprogramsthatwereinsevenPhase1or2clinicaltrialsin2008/09:KB001isananti-infectiveforPseudomonasaeruginosainfectionsbeingtestedincysticfibrosisandinintensivecarepatientsonaventilator,andKB002andKB003arebeingevaluatedininflammatoryconditions,suchasrheumatoidarthritisandasthma.KB004isinpreclinicaldevelopmentforoncology,andthecompanyplanstofileanINDforitin1H2010.Thecompany抯Humaneering?technologyoffersadvantagesoverothermethodsofhumanantibodycreationintermsofimmunogenicity,potency,andmanufactur